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Certain precautions must be exercised when supplementing with arginine:

-Diabetics and borderline diabetics should use arginine with care because it may worsen diabetes.
-Children, teenagers, and pregnant or lactating women should not use arginine (or growth hormone stimulators) except under the care of a knowledgeable physician.
-Arginine sometimes reactivates latent herpes virus infections. Those with ocular or brain herpes should avoid it. Persons with herpes benefit from lysine which competes with arginine in amino acid metabolism. If you have herpes and use arginine at all, use lysine at a separate time of day on an empty stomach to avoid lysine depletion and herpes exacerbations.
-Arginine should be used with care in those with psychosis because they may experience a worsening of symptoms.
-Arginine should always be taken with antioxidants.

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